Call us: 028 6632 8200 Email us: info@lindaburke.co.uk   
Small Intestinal Bacterial Overgrowth

Small Intestinal Bacterial Overgrowth

Small Intestinal Bacterial Overgrowth

What is SIBO?

SIBO, small intestinal bacterial overgrowth, is defined as an increase in the number of bacteria, and/or changes in the types of bacteria present in the small bowel. In most patients, SIBO is not caused by a single type of bacteria, but is an overgrowth of the various types of bacteria that should normally be found in the colon . Less commonly, SIBO results from an increase in the otherwise normal bacteria of the small bowel.

With SIBO, that overly prolific and displaced bacterial population creates a chronic bacterial infection. The excess bacteria begins feeding on the digesting food, fermenting and multiplying, and creating gas as a byproduct. It's that fermentation that can result in that ballooning and bloating belly as well as motility disruptions.
SIBO can result from bacteria seeping through a leaky ileocecal valve. (Remember your anatomy? That valve is the one that separates the ileum, or last part of the small intestine, from the colon!) The bacteria then moves into the distal region of the ileum and sometimes up to the jejunum, the place where most of the absorption takes place. And when the conditions are just right, that bacteria can grow to unhealthy levels. You can just begin to consider how things may go awry.
Bacterial populations are normally kept at bay by acid secretion in the stomach, the migrating motor complex (MMC) which moves chyme through the digestive tract with peristaltic waves between meals, and the ileocecal valve which prevents contents from the colon from entering the small intestine.

Risk factors for SIBO
• Low stomach acid
• Irritable bowel syndrome
• Celiac disease (long-standing)
• Crohn’s disease
• Prior bowel surgery
• Diabetes mellitus (type I and type II)
• Multiple courses of antibiotics
• Organ system dysfunction, such as liver cirrhosis, chronic pancreatitis, or renal failure

Moderate alcohol consumption and oral contraceptive pills (OCPs) also increase the risk for SIBO
Heavy alcohol use has long been recognized in association with SIBO A study also found an association between SIBO and moderate alcohol consumption, defined as up to one drink per day for women and two drinks per day for men. Alcohol appears to have effects on several of the normal protective mechanisms, including causing injury to the small bowel mucosal cells, contributing to leaky gut, and decreasing the muscular contractions. Additionally, alcohol may “feed” a few specific types of bacteria contributing to overgrowth .

Overall there appears to be a moderate association between OCPs and inflammatory bowel disease (IBD) such as Crohn’s disease (5). Though no studies to date specifically correlate the use of OCPs with SIBO, given the known relationship between IBD and SIBO, it is likely that this association holds true for SIBO as well. However, once patients stop taking OCPs, this risk appears to reverse.

Approximately one in five adults in the United Kingdom has IBS (Irritable Bowel Syndrome). It's now estimated that 80% of IBS sufferers likely have SIBO.
The typical symptoms of IBS are much the same as those of SIBO, which is what can make this process of diagnosing somewhat confusing. We don't want to jump to conclusions, but we do want to consider the options, as the ways in which we might address different forms of IBS may be varied.

SIBO has been shown to negatively affect both the structure and function of the small bowel. It may significantly interfere with digestion of food and absorption of nutrients, primarily by damaging the cells lining the small bowel (the mucosa). Additionally, this damage to the small bowel mucosa can lead to leaky gut (when the intestinal barrier becomes permeable, allowing large protein molecules to escape into the bloodstream), which is known to have a number of potential complications including immune reactions that cause food allergies or sensitivities, generalized inflammation, and autoimmune diseases .

These pathogenic bacteria, whether too many or the wrong types, can lead to nutritional deficiencies on top of those due to poor digestion or absorption. In particular, the bacteria will take up certain B vitamins, such as vitamin B12, before our own cells have a chance to absorb these important nutrients. They may also consume some of the amino acids, or protein, that we’ve ingested, which can lead to both mild protein deficiency and an increase in ammonia production by certain bacteria. (We normally produce some ammonia daily from normal metabolism, but ammonia requires detoxification, so this may add to an already burdened detoxification system.) The bacteria may also decrease fat absorption through their effect on bile acids, leading to deficiencies in fat soluble vitamins like A and D.

What causes SIBO?

The body has several different ways of preventing SIBO. These include gastric acid secretion (maintaining an acidic environment), waves of bowel wall muscular activity, immunoglobulins in the intestinal fluid, and a valve that normally allows the flow of contents into the large bowel but prevents them from refluxing back into the small bowel. (This is called the ileocecal valve because it’s located between the ileum, or terminal end of the small intestine, and the cecum, a pouch forming the first part of the large bowel.)

The cause of SIBO is usually complex, and likely affects more than one of the protective mechanisms listed above.  A number of risk factors for SIBO have been identified, with some of the more common risk factors listed below.  For a more complete discussion of associated diseases and risk factors check out this studyand this study.

Risk factors for SIBO

• Low stomach acid
• Irritable bowel syndrome
• Celiac disease (long-standing)
• Crohn’s disease
• Prior bowel surgery
• Diabetes mellitus (type I and type II)
• Multiple courses of antibiotics
• Organ system dysfunction, such as liver cirrhosis, chronic pancreatitis, or renal failure
•Moderate alcohol consumption and oral contraceptive pills (OCPs) also increase the risk for SIBO
Heavy alcohol use has long been recognized in association with SIBO A study also found an association between SIBO and moderate alcohol consumption, defined as up to one drink per day for women and two drinks per day for men. Alcohol appears to have effects on several of the normal protective mechanisms, including causing injury to the small bowel mucosal cells, contributing to leaky gut, and decreasing the muscular contractions. Additionally, alcohol may “feed” a few specific types of bacteria contributing to overgrowth

.
Overall there appears to be a moderate association between OCPs and inflammatory bowel disease (IBD) such as Crohn’s disease (5). Though no studies to date specifically correlate the use of OCPs with SIBO, given the known relationship between IBD and SIBO, it is likely that this association holds true for SIBO as well. However, once patients stop taking OCPs, this risk appears to reverse.


How do you know if you have SIBO?

The number of people with SIBO in the general population remains unknown. Some studies suggest that between 6 to 15% of healthy, asymptomatic people have SIBO, while up to 80% of people with irritable bowel syndrome (IBS) have SIBO .

SIBO is largely under-diagnosed. This is because many people don’t seek medical care for their SIBO symptoms, and because many doctors aren’t aware of how common SIBO is. Complicating this, the most commonly used tests (breath tests measuring levels of hydrogen and methane gas) still have fairly high rates of false negatives (meaning the test results come back as negative but you actually do have the disease)

The most common symptoms of SIBO include:

• Abdominal pain/discomfort
• Bloating and abdominal distention
• Diarrhea
• Constipation (generally associated with methanogens
• Gas and belching
• In more severe cases, there may be weight loss and symptoms related to vitamin deficiencies.

Why SIBO can be difficult to treat

Antibiotics are often used to treat SIBO. However studies show that despite treatment with antibiotics, recurrence develops in almost half of all patients within one year.   Comparing treatment with rifaximin (the most commonly used antibiotic for SIBO) and botanical antimicrobials showed slightly better outcomes with the botanical protocol, but still with successful treatment in close to only half of all patients after one course of treatment.

These finding suggests that treatment of the overgrowth alone is not enough for most people. An additional piece of successful treatment must include addressing the underlying cause, or predisposing factor.

Though there are many identified associations between SIBO and other diseases as described above, abnormalities in gut motility are recognized as one of the most common associations. One study published this month demonstrated that patients with SIBO do have significant delays in small bowel transit time (the amount of time it takes something to move through the small bowel). This finding suggests that patients with SIBO, who do not recover after a standard course of antibiotics, or botanical antimicrobial protocol (which I prefer), may benefit from the addition of a prokinetic agent, which increases the muscular contractions of the small bowel.
 

The Health Transformer Approach


Meta Health Scan 5 Step Protocol

In every case of Osteoporosis there is an underlying cause…something individual to each person.   If at one time you didn’t have these symptoms and now do, obviously something has changed in your system in order that these symptoms have been produced.   Osteoporosis is merely a symptom of the underlying cause.   To treat Osteoporosis  effectively and naturally we need to address the cause. In this centre we specialize in root cause diagnosis of any health condition using our state of the art Meta Health Scan. 

5 Step Protocol
1. Detect (In-Depth Evaluation & Advanced Testing)
2. Detox (Heavy Metals, Chemicals, Hydrocarbons, Bleaches, EMF)
3. Eliminate (Pathogens…virus, post virus, bacteria, parasites, fungi)
4. Rebuild (Tissues & Pathways)
5. Rebalance organs (kidneys, liver, etc.)

The 5 Steps to Restoring Health Protocol had been developed following many years of research and experience and utilizes food, nutritional supplements, herbal and energetic formula
The Meta Health Scan is carried out utilizing the amazing diagnostic ability of Clinical Kinesiology.   It is reliable, accurate and reproducible. The scan will reveal the imbalances unique to your body, and how these are affecting you.   The scan reveals such issues as endogenous bio-toxicity, nutrient imbalances or deficiencies, sub-clinical infections, allergies and food sensitivities.  We also test for organ imbalances, hormone imbalance, and leaky gut.    Any abnormality in these areas will easily be picked up during the Health Scan. We also examine your entire lifestyle, sleep quality and any emotional/psychological contributors to your condition.

In-Depth Consultation regarding your results.

Once this information is gathered we offer you an in-depth consultation to discuss your results, during which we discuss what has been revealed by the scan, where and how this has arisen, and how to remove or transform it, and reboot your system.   I believe it is very important for each person to understand what has been going on in their body, how the condition has developed, and how to unravel and resolve it naturally.   My intention is not just to teach you about your condition, but more importantly to empower you with understanding in order that you are able to take back control of your health.

Individually tailored Treatment Plan

Together we create an individualized tailored treatment plan for you.   This may include some or all of there: a gentle detoxification protocol, dietary changes, specific supplements, life style changes, exercise, etc tailored to your specific needs. In the majority of cases treatment can be implemented by you at home without the need for repeated visits to the centre; however Health Coaching and support is built in to this package to assist you through your treatment.

Supportive Treatments

Once on the prescribed treatment, some clients choose to support their system with other therapies toastiest healing.   This is not essential but will speed up your progress.   These include;

 

all of which are on offer at this centre.
I am delighted to be able to report that the results our client’s achieve with this approach are outstanding and lasting in the vast majority of cases.